diff --git a/CHANGES.rst b/CHANGES.rst
index adf2623d..bcec74a7 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -3,6 +3,8 @@ Version 2.3.0
 
 Unreleased
 
+-   Ensure subdomains are applied with nested blueprints. :issue:`4834`
+
 
 Version 2.2.3
 -------------
diff --git a/docs/blueprints.rst b/docs/blueprints.rst
index af368bac..d5cf3d82 100644
--- a/docs/blueprints.rst
+++ b/docs/blueprints.rst
@@ -140,6 +140,19 @@ name, and child URLs will be prefixed with the parent's URL prefix.
     url_for('parent.child.create')
     /parent/child/create
 
+In addition a child blueprint's will gain their parent's subdomain,
+with their subdomain as prefix if present i.e.
+
+.. code-block:: python
+
+    parent = Blueprint('parent', __name__, subdomain='parent')
+    child = Blueprint('child', __name__, subdomain='child')
+    parent.register_blueprint(child)
+    app.register_blueprint(parent)
+
+    url_for('parent.child.create', _external=True)
+    "child.parent.domain.tld"
+
 Blueprint-specific before request functions, etc. registered with the
 parent will trigger for the child. If a child does not have an error
 handler that can handle a given exception, the parent's will be tried.
diff --git a/src/flask/blueprints.py b/src/flask/blueprints.py
index f6d62ba8..2403be1c 100644
--- a/src/flask/blueprints.py
+++ b/src/flask/blueprints.py
@@ -358,6 +358,9 @@ class Blueprint(Scaffold):
         :param options: Keyword arguments forwarded from
             :meth:`~Flask.register_blueprint`.
 
+        .. versionchanged:: 2.3
+            Nested blueprints now correctly apply subdomains.
+
         .. versionchanged:: 2.0.1
             Nested blueprints are registered with their dotted name.
             This allows different blueprints with the same name to be
@@ -453,6 +456,17 @@ class Blueprint(Scaffold):
         for blueprint, bp_options in self._blueprints:
             bp_options = bp_options.copy()
             bp_url_prefix = bp_options.get("url_prefix")
+            bp_subdomain = bp_options.get("subdomain")
+
+            if bp_subdomain is None:
+                bp_subdomain = blueprint.subdomain
+
+            if state.subdomain is not None and bp_subdomain is not None:
+                bp_options["subdomain"] = bp_subdomain + "." + state.subdomain
+            elif bp_subdomain is not None:
+                bp_options["subdomain"] = bp_subdomain
+            elif state.subdomain is not None:
+                bp_options["subdomain"] = state.subdomain
 
             if bp_url_prefix is None:
                 bp_url_prefix = blueprint.url_prefix
diff --git a/tests/test_blueprints.py b/tests/test_blueprints.py
index 1bf130f5..dbe00b97 100644
--- a/tests/test_blueprints.py
+++ b/tests/test_blueprints.py
@@ -950,6 +950,55 @@ def test_nesting_url_prefixes(
     assert response.status_code == 200
 
 
+def test_nesting_subdomains(app, client) -> None:
+    subdomain = "api"
+    parent = flask.Blueprint("parent", __name__)
+    child = flask.Blueprint("child", __name__)
+
+    @child.route("/child/")
+    def index():
+        return "child"
+
+    parent.register_blueprint(child)
+    app.register_blueprint(parent, subdomain=subdomain)
+
+    client.allow_subdomain_redirects = True
+
+    domain_name = "domain.tld"
+    app.config["SERVER_NAME"] = domain_name
+    response = client.get("/child/", base_url="http://api." + domain_name)
+
+    assert response.status_code == 200
+
+
+def test_child_and_parent_subdomain(app, client) -> None:
+    child_subdomain = "api"
+    parent_subdomain = "parent"
+    parent = flask.Blueprint("parent", __name__)
+    child = flask.Blueprint("child", __name__, subdomain=child_subdomain)
+
+    @child.route("/")
+    def index():
+        return "child"
+
+    parent.register_blueprint(child)
+    app.register_blueprint(parent, subdomain=parent_subdomain)
+
+    client.allow_subdomain_redirects = True
+
+    domain_name = "domain.tld"
+    app.config["SERVER_NAME"] = domain_name
+    response = client.get(
+        "/", base_url=f"http://{child_subdomain}.{parent_subdomain}.{domain_name}"
+    )
+
+    assert response.status_code == 200
+
+    response = client.get("/", base_url=f"http://{parent_subdomain}.{domain_name}")
+
+    assert response.status_code == 404
+
+
 def test_unique_blueprint_names(app, client) -> None:
     bp = flask.Blueprint("bp", __name__)
     bp2 = flask.Blueprint("bp", __name__)