diff --git a/src/flask/app.py b/src/flask/app.py
index 6b0e2c1e..0ad32e49 100644
--- a/src/flask/app.py
+++ b/src/flask/app.py
@@ -1221,7 +1221,7 @@ class Flask(App):
         return rv
 
     def _unpack_response_tuple(
-        self, rv: tuple
+        self, rv: tuple[t.Any, ...]
     ) -> tuple[ft.ResponseReturnValue, int | None, HeadersValue | None]:
         """Unpack a response tuple into body, status, and headers.